Spheroidal and nanocrystal structures created from carbodiimide crosslinking reaction with RADA16

Monreal, Jorge
Hyde, Robert
RADA16 is a widely studied polypeptide known for its ability to self-assemble intob-sheets that form nanofibers. Here we show that it is possible to self-crosslink the molecule via 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC) as aqueous solutions. The product results in a mix of nanocrystals and near micron-size spherules. SEM and TEM pictures provide a view of the structures and nano tracking analysis gives their size distributions. FTIR analysis provides evidence for the existence of a crosslinking reaction.
Chi tiết xin mời tham khảo tại http://repository.vnu.edu.vn/handle/VNU_123/58210
Title: Spheroidal and nanocrystal structures created from carbodiimide crosslinking reaction with RADA16
Authors: Monreal, Jorge
Hyde, Robert
Keywords: RADA16;Crosslinking;EDC;Spherule
Issue Date: 2017
Publisher: H. : ĐHQGHN
Description: p. 178-182
URI: http://repository.vnu.edu.vn/handle/VNU_123/58210
ISSN: 2468-2284
Appears in Collections:Advanced Materials and Devices

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